olivetolic acid
- Product Name
- olivetolic acid
- CAS No.
- 491-72-5
- Chemical Name
- olivetolic acid
- Synonyms
- Olivetolcarboxylic acid;2,4-Dihydroxy-6-pentylbenzoic acid;139400;olivetolic acid;olivanic acid powder 98%;Benzoic acid, 2,4-dihydroxy-6-pentyl-;Olivetolic acid 1000 μg/mL in Methanol
- CBNumber
- CB81340565
- Molecular Formula
- C12H16O4
- Formula Weight
- 224.25
- MOL File
- 491-72-5.mol
olivetolic acid Property
- Melting point:
- 143 °C
- Boiling point:
- 403.9±25.0 °C(Predicted)
- Density
- 1.237±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.41±0.34(Predicted)
- form
- Solid
- color
- Light Beige to Light Brown
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16)
- InChIKey
- SXFKFRRXJUJGSS-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=C(CCCCC)C=C(O)C=C1O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 26282
- Product name
- Olivetolic Acid
- Packaging
- 25mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 26282
- Product name
- Olivetolic Acid
- Packaging
- 5mg
- Price
- $31
- Updated
- 2023/06/20
- Product number
- O533005
- Product name
- OlivetolicAcid
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- O533005
- Product name
- OlivetolicAcid
- Packaging
- 500mg
- Price
- $490
- Updated
- 2021/12/16
- Product number
- PXT0005334
- Product name
- OLIVETOLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.01
- Updated
- 2021/12/16
olivetolic acid Chemical Properties,Usage,Production
Uses
Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol.
Definition
ChEBI: A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively.
Biosynthesis
Olivetolic acid (OLA) biosynthesis involves the condensation of one hexanoyl-CoA with three malonyl-CoAs by a type III PKS (tetraketide synthase) OLA synthase (C. sativa OLS; CsOLS) and an OLA cyclase (CsOAC), both enzymes were derived from the Cannabis species (C. sativa). Studies have achieved trace amount of OLA production in both E. coli and S. cerevisia[1]. Ma et al. find that Pseudomonas sp LvaE encoding a short-chain acyl-CoA synthetase can efficiently convert hexanoic acid to hexanoyl-CoA. The co-expression of the acetyl-CoA carboxylase, the pyruvate dehydrogenase bypass, the NADPH-generating malic enzyme, as well as the activation of peroxisomal β-oxidation pathway and ATP export pathway are effective strategies to redirect carbon flux toward OLA synthesis.
References
[1] Ma, J, Y. Gu, and P. Xu . "Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica." Cold Spring Harbor Laboratory(2021).
olivetolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
olivetolic acid Suppliers
View Lastest Price from olivetolic acid manufacturers
- Product
- olivetolic acid 491-72-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 3000kg
- Release date
- 2023-12-08
- Product
- olivetolic acid 491-72-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- olivetolic acid 491-72-5
- Price
- US $1.00/KG
- Min. Order
- 100g
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2019-12-17